Recombinant factor VIII (rFVIII) is the antihaemophilic factor A, obtained using recombinant DNA technology. With this technology, pure protein is synthesized in the laboratory instead of being extracted from blood.
In the following pages, it will be explained in detail how the knowledge and analysis of DNA, using the new instruments of molecular genetics, have represented both the beginning and follow-up stages in the development of recombinant FVIII.
|
